摘要
目的:探究影响胆道闭锁患儿术后黄疸消退的相关因素。方法:选取2004-2008年在笔者所在医院进行肝门空肠吻合手术治疗的胆道闭锁患儿40例,术后存在黄疸的为观察组,共16例,黄疸消退的为对照组,共24例,选取正常体检的儿童16例,测定三组儿童血清内毒素和透明质酸的水平及肝功能相关指标,并进行比较分析。结果:三组儿童中,正常体检儿童血清内毒素和透明质酸的水平较胆道闭锁患儿术后的水平低,而在胆道闭锁手术后的患儿中,存在黄疸的患儿比黄疸消退的患儿血清内毒素和透明质酸的水平高,且胆道闭锁患儿术后肝功能各项指标均与正常体检的儿童比较,差异有统计学意义(P<0.05)。结论:对于胆道闭锁患儿来说,术后黄疸是否消退与血清中内毒素和透明质酸的水平密切相关,可作为判断术后黄疸是否消退的指标在临床推广。
Objective： To explore related factors influencing jaundice in children with biliary atresia operation.Method： Selected 40 cases of biliary atresia treated in our hospital, a total of 16 cases with jaundice as observation group, a total of 24 cases without jaundice as control group, and then we selected 16 cases of normal healthy children, and examed the serum endotoxin and hyaluronic acid level.Result： The serum endotoxin and hyaluronic acid level in normal children was lower than children with biliary atresia operation.While in children after biliary atresia, the serum endotoxin and hyaluronic acid level in children with jaundice was higher than children without jaundice, the difference was statistically significant（P〈0.05）.Conclusion： For children with biliary atresia, jaundice is closely related to the serum endotoxin and hyaluronic acid level, and it can be used as a jaundice extinction index in clinical application.
出处
《中外医学研究》
2013年第28期17-18,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
胆道闭锁
术后
黄疸
Biliary atresia
After operation
Jaundice
