腹腔镜手术治疗胃的胃肠间质瘤

Laparoscopic surgery of gastric gastrointestinal stromal tumor

胃肠问质瘤（gastrointestinalstromaltumor，GIST）是消化道最常见的问叶组织源性肿瘤，因该肿瘤独特的生物学行为和临床特征，外科手术和分子靶向治疗是胃GIST主要治疗手段。腹腔镜技术因其具有微创的特点。已逐渐用于胃GIST的手术治疗，并成为胃GIST外科治疗的发展趋势。本文就规范实施腹腔镜胃GIST手术中．需掌握的手术适应证、手术原则、手术方式、术中定位以及外科联合靶向药物治疗原则等进行论述，以期为临床治疗提供参考。

Gastric gastrointestinal stromal tumor（GIST） is the most common mesenchymal neoplasms of the gastro- intestinal tract.For its unique biological behavior with KIT gene expression and the particular clinical characteristics with the recurrent nature, surgery and molecular targeted therapy is the main treatment of gastric GIST. Laparoscopic technology has been used in the surgical treatment of gastric GIST and is the future trend. In this article, we shed some light on the standardize surgical procedures of radical laparoscopic gastrec, tomy, obeying the surgical principles, accurate intraoperative localization, and surgery combined with targeted therapy.