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慢性肾脏病患者内脂素和白介素18水平与胰岛素抵抗和微炎性反应状态的相关性 被引量:3

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摘要 胰岛素抵抗(IR)和慢性微炎性反应是影响慢性肾脏病(CKD)进展的两个主要因素。IR在CKD患者中很常见,早期CKD患者体内即存在IR,随着病情进展逐渐加重,且可加速。肾脏疾病的进展。近年研究发现脂肪细胞因子内脂素(Visfatin)在CKD患者IR的发生发展中起重要作用。
出处 《中华肾脏病杂志》 CAS CSCD 北大核心 2013年第8期625-626,共2页 Chinese Journal of Nephrology
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  • 1Moschen AR, Kasser A, Enrich B, et al. Visfatin, an Adipocytokine with Proinflammatory and Immunomodulating Properties. J Immunol, 2007, 178: 1748-1758.
  • 2Opstad TB, Pettersen A, Amesen H, et al. Circulating levels ofIL-18 are significantly influenced by the IL-18 + 183 A/G polymorphism in coronary artery disease patients with diabetes type 2 and the metabolic syndrome: an observational study. Cardiovasc Diabetol, 2011, 10:110-118.
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