FOXP3与慢性肝病的研究进展被引量：1

Update of FOXP3 and chronic liver diseases

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摘要叉状头转录因子P3 （forkhead box P3,FOXP3）是脊椎动物叉头样/翼状螺旋（forkhead/winged-helix,FKH）家族的一个新成员,作为调节性T淋巴细胞（regulatory Tcell,Treg）特异性标志,通过调节Treg、非Treg的功能以及调节细胞因子表达等多种方式参与维持机体的免疫稳态.近年国内外大量研究表明FOXP3与自身免疫性肝病、病毒性肝炎等多种肝脏疾病的发生和发展有关,本文将FOXP3与慢性肝病近年研究进展作一综述.

作者张宏伟姚冬梅

机构地区河北医科大学第二医院消化内科

出处《中华肝脏病杂志》 CAS CSCD 北大核心 2013年第10期792-795,共4页 Chinese Journal of Hepatology

关键词肝疾病 T淋巴细胞调节叉状头转录因子P3 Liver diseases T-Lymphocytes, regulatory Forkhead box P3

分类号 R575 [医药卫生—消化系统]

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