腹腔镜与开腹直肠癌切除术近期临床疗效的对比研究

A comparative study of the short-term outcomes between laparoscopic resection and open resection for rectal cancer

目的比较腹腔镜与开腹直肠癌切除术的近期临床疗效，探讨腹腔镜直肠癌切除术的安全性和可行性。方法回顾性分析68例行直肠癌切除术患者的临床资料，根据手术方式不同分为腹腔镜组31例和开腹组37例。结果两组在淋巴结清扫数目和术后并发症方面比较差异无统计学意义（P〉0．05）。腹腔镜组的手术时间明显长于开腹组[（162．03±39．78）min比（142．70±30．29）min]，术中出血量明显少于开腹组[（153．23±58．94）ml比（247．46±92．51）m1]，肠功能恢复时间和住院时间明显短于开腹组[（51．39±7．28）h比（77．81±11．68）h、（12．65±2．24）d比（15．29±3．11）d]，差异均有统计学意义（P〈0．05或〈0．01）。结论腹腔镜直肠癌切除术可达到与传统开腹手术相似的近期临床疗效，而且在安全性及术后恢复方面更具优势，值得进一步推广。

Objective To compare the clinical efficacy between laparoscopic resection and open resection for rectal cancer and explore the safety and feasibility of laparoseopie resection. Methods The clinical data of 68 patients suffering rectal cancer resection were analyzed retrospectively. The patients were divided into laparoscopie group （31 cases） and open group （37 cases） according to the operation method. Results There was no significant difference in the number of lymph nodes dissection and postoperative complication rate between two groups （P 〉 0.05 ）. The operation time in laparoscopic group was significantly longer than that in open group [（162.03 ±39.78） min vs. （142.70 ±30.29） mini. The bleeding in laparoscopic group was less than that in open group [ （153.23 ± 58.94） ml vs. （247.46 ± 92.51 ） ml]. The recovery of intestinal function time and hospital stay in laparoscopic group was shorter than that in open group [（51.39 ±7.28 ） h vs. （77.81 ±11.68） h, （12.65 ±2.24） d vs. （15.29 ±3.11） d]. And there were significant differences between two groups （P 〈 0.05 or 〈 0.01 ）. Conclusion Laparoscopic resection for rectal cancer can achieve short-term clinical efficacy similar to the traditional open surgery, and advantages in terms of safety and postoperative recovery worthy of further promotion.