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子宫内膜干细胞研究进展 被引量：1

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摘要 子宫内膜由功能层和基底层组成，其功能层随卵巢激素而发生周期性变化，在女性生育期可发生超过400次的增生、分化及脱落，显现出活跃、强大的再生能力。早在上世纪七十年代，Prianishnik—OV[1]就提出了子宫内膜干细胞的假说，认为参与子宫内膜功能层增生修复的是一类具有高度增殖、自我更新和分化潜能的内膜干细胞。目前随着干细胞研究的发展，通过细胞克隆、干细胞分离鉴定、诱导分化等研究证实在子宫内膜、蜕膜及月经血中均存在干细胞，
作者 王秋石 曲雯雯 黄薇
机构地区 四川大学华西二院妇产科
出处 《妇产与遗传（电子版）》 2013年第2期50-54,共5页 Obstetrics-Gynecology and Genetics (Electronic Edition)
关键词 子宫内膜功能 干细胞 分化潜能 周期性变化 卵巢激素 再生能力 自我更新 细胞克隆
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
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参考文献40

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二级参考文献9

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共引文献2

同被引文献29

  • 1Ghobadi F, Mehrabani D, Mehrabani G. Regenerative potentialof endome~al stem cells .. a mini review. World J Plast Surg, 2015, 4: 3-8.
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  • 7Dimitrov R, Kyurkchiev D, Timeva T, et al. First-trimester human decidua contains a population of mesenchymai stem cells. FertilSteril, 2010, 93.. 210-219.
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  • 10Miyazaki K, Maruyama T, Masuda H, et al. Stem cell-like differentiation potentials of endometrial side population cells as revealed by a newly developed in vivo endometrial stem cell assay. PLoSone, 2012, 7: e50749.

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妇产与遗传（电子版）
2013年 第2期

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