文冠果种皮化学成分的分离与鉴定

Isolation and identification of chemical constituents from the testa of Xanthoceras sorbifolia Bunge

目的对文冠果（Xanthoceras sorbifolia Bunge）种皮乙醇提取物的化学成分进行研究。方法采用硅胶柱色谱、Sephadex LH-20凝胶柱色谱等方法进行分离纯化，根据化合物的理化性质和波谱数据进行结构鉴定。结果从文冠果种皮中分离得到8个已知化合物，分别鉴定为：秦皮素（fraxetin，1）、秦皮苷（fraxin，2）、异嗪皮啶（isofraxidin，3）、原儿茶酸（protocatechuicacid，4）、香草酸（vanillicacid，5）、对甲氧基苯甲酸（4-methoxy-benzoic acid，6）够-谷甾醇（β-simsterol，7）、胡萝卜苷（daucosterol，8）。结论化合物3—7均为首次从文冠果种皮中分离得到，化合物6为首次从该属植物中分离得到。

To isolate the bioactive constituents of testa from Xanthoceras sorbifolia Bunge, the active fractions were purified by chromatography on silica gel column and Sephadex LH-20 column. The structure elucidation of eight compounds were carried out by analysis of the physico-chemical constants and the NMR data. They were identified as fraxetin （ 1 ）, fraxin （ 2 ）, isofraxidin （ 3 ）, protocatechuic acid （ 4 ）, vanillic acid （5） ,4-methoxybenzoic acid（6 ） ,β-sitosterol （ 7 ） and daucosterol （ 8 ）. Compounds 3 - 7 were isolated from the testa of Xanthoceras sorbifolia firstly and compound 6 has been reported from this genus for the first time.