中西医结合治疗子宫肌瘤的临床观察

Clinical Observation on Chinese and Western Medicine in Treatment of Hysteromyoma

目的:探讨米非司酮联合血府逐瘀颗粒治疗子宫肌瘤的临床效果,并对护理干预措施进行分析与总结。方法:选择我院收治的80例子宫肌瘤患者的临床资料,其中,观察组40例患者采用米非司酮联合血府逐瘀颗粒进行治疗,同时予以相应的护理措施,而对照组患者40例患者采用常规治疗措施,比较两组患者的临床效果。结果:(1)两组治疗后子宫及肌瘤体积均较治疗前明显减小,血红蛋白明显升高,有显著性差异(P<0.05),且治疗组子宫和肌瘤体积减小程度较对照组更为明显,差异有统计学意义(P<0.05)。(2)两组患者血清P、FSH、LH及E2水平均较治疗前均明显下降(P<0.05),组间比较血清P、FSH、LH差异有统计学意义(P<0.05)。(3)经秩和检验,治疗组的临床疗效显著优于对照组(P<0.01)。(4)不良反应情况:两组不良反应发生率比较差异无统计学意义(P>0.05)。结论:米非司酮联合血府逐瘀颗粒治疗子宫肌瘤具有调节人体内分泌、活血化瘀、滋阴补肾、软坚散结、理气止痛等功效,可有效缩小肌瘤体积,改善临床症状,疗效确切且无明显不良反应,为子宫肌瘤患者提供了一个安全的治疗方法,值得临床推广应用。

Objective ： To discuss the effect of Mifepristone combined with Xufu Zhuyu Granules in the treatment of hysteromay- oma and to study and summarize the nursing intervention. Methods ：80 cases of hysteromayoma patients in our hospital were select- ed. 40 cases in observation group were treated with Mifepfistone combined with Xufu Zhuyu Granules and given the corresponding nursing intervention at the same time. While 40 cases in control group were treated with routine therapy. The effects of two groups were compared. Results ： （ 1 ） After treatment, the uterus and hysteromayoma volmne were both decreased and hemoglobin was in- creased with significant difference（ P 〈 0. 05 ）. The decrease of the uterus and hysteromayoma volume in treatment group was more obvious than that of control group with significant difference. （2） The levels of P, FSH, LH ar,d E2 in serum in two groups were all obviously decreased（ P 〈0.05）. The comparisons of P,FSH and LH in serum had significant difference（ P 〈 0. 05 ）. （3）By rank -sum test,the effect of treatment group was superior to that of control group（ P 〈 0. 01 ）. （4）Adverse reactions：the occurrences of adverse reactions in two groups had no significant difference （ P 〉 O. 05 ）. Conclusion ： Mifepristone combined with Xufu Zhuyu Granules in the treatment of hysteromayoma can regulate endocrine,promote blood circulation and resolve stasis,nourish Yin and invigorate kidney,soften and disperse mass,regulate Qi and relieve pain. It can shorten the volume of hysteromayoma and improve the clinical symptoms without adverse reactions,providing a safe treatment which is worthy of application for hysteromayoma.