摘要
目的:探讨平消胶囊同步放疗在食管癌术后放疗的应用价值。方法:84例食管癌术后三维适形放疗(3D-CRT)患者分为两组,39例(试验组)放疗同步口服平消胶囊,每天3次,每次5粒;45例(对照组)仅单纯术后放疗。结果:随访率95.2%。实验组1、3年总生存率(OS)为90.4%、70.5%,中位生存期35个月;对照组1、3年OS为82.2%、47.9%,中位生存期23个月,差异有显著性(P=0.020)。实验组1、3年无病生存率(DFS)为87.2%、66.1%,中位无病生存期33个月;对照组DFS为66.7%、44.4%,中位无病生存期20个月,差异有统计学意义(P=0.028)。结论:平消胶囊同步放疗可以提高食管癌术后疗效,有放疗增敏作用。
Objective:To investigate the value of combination of Pingxiao capsule and radiotherapy on the radical esophagectomy of esophageal carcinoma. Methods: All 84 patients with esophageal carcinoma undergone radical esophagectomy were divided into two groups,39 patients in experiment group treated by combination of Pingxiao cap- sule and radiotherapy,45 patients in control group treated by radiotherapy alone. Results:The following- up rate was 95.2%. The 1 - ,3 -year OS were 90.4% ,70.5% for experiment group, the median overall survival time was 35 months ;The 1 - ,3 -year OS were 82.2% ,47.9% for control group,the median overall survival time was 23 months (P = 0.020). The 1 - ,3 -year DFS were 87.2% ,66.1% for experiment group, the median disease -free time was 33 months;The 1 - ,3 -year DFS were 66.7% ,44.4% for control group, the median disease -free time was 20 months ( P = 0. 028 ). Conclusion: Combination of Pingxiao capsule and radiotherapy can elevate effect and has sensi- tization of radiotherapy.
出处
《现代肿瘤医学》
CAS
2013年第10期2248-2250,共3页
Journal of Modern Oncology
关键词
食管肿瘤
手术
放射治疗
平消胶囊
esophageal neoplasms
surgery
radiotherapy
pingxiao capsule