超声引导下肝癌射频消融术的疗效及其对患者生命质量的影响

Efficiency of ultrasound-guided percutaneous radiofrequency ablation and its influence of quality of life for patients with heptatic cancer

目的:观察超声引导下肝癌射频消融术的疗效及其对患者生命质量的影响。方法:92例肝癌143个病灶行超声引导下射频消融术治疗。于围手术期给予患者综合护理,分别于术前、术后进行血清学和影像学检查,并应用肝癌生命质量量表测定生命质量。结果:97.9%的肝癌患者RFA术后症状有不同程度的改善,未出现严重并发症。转氨酶出现一过性升高,并于术后一周恢复,AFP水平较术前明显下降。肝癌病灶完全消融率71.3%,不全消融率28.7%。术后1年、2年的总生存率分别为90.7%、73.2%。结论:RFA是一种有效、安全、副作用小的肝癌非手术治疗手段,能够提高患者生命质量。围手术期的综合护理对于RFA顺利实施及术后的康复具有重要作用。

Objective：To observe the clinical efficacy of uhrasound -guided percutaneous radiofrequency ablation and its influence of quality of life for patients with hepatic cancer. Methods ： All 92 hepatic cancer patients underwent ultrasound- guided percutaneous radiofrequency ablation were reviewed retrospectively, 143 lesions were treated. Comprehensive care was given to patients perioperatively. Serological and radiologieal detections were done before and after the surgery, and assessed the quality of life using General Questionnaire and Quality of life Scale for liver cancer patients. Results ： Symptoms of 97.9% liver cancer patients got various degrees of relief postoperatively and no serious complications ,The level of transaminase increased transiently and recovered after a week. AFP level decreased signifi- cantly compared with the preoperation. HCC lesions complete ablation rate was 71.3%, the insufficiency ablation rate was 28.7%. 1 - year and 2 - year overall survival rates were 90.7% ,73.2% respectively. Conclusion： RFA is an ef- fective, safe, little side effect non - surgical treatment of liver cancer which can improve the quality of life of patients. Comprehensive care plays an important role in successful completion of RFA and postoperative rehabilitation.