卵巢癌化疗后感染现状和影响因素分析

Study on infection status and influential factors of ovarian cancer patients after chemotherapy

目的探讨卵巢癌患者化疗后感染现状和影响因素。方法选取2011年1月至2013年1月收治的302例卵巢癌患者的临床资料,进行描述性统计和二分类Logistic回归分析。结果卵巢癌患者化疗后感染发生率为10.6%(32/302),以上呼吸道感染最多见(37.5%),多因素Logistic回归分析发现,高龄(OR=7.692,P=0.000)、侵入性操作多(OR=13.074,P=0.000)、白细胞数低(OR=15.864,P=0.000)和住院时间>21天(OR=10.033,P=0.000)是卵巢癌患者化疗后感染的影响因素。结论卵巢癌患者化疗后感染发生率较高,其发生受多方面因素影响。

Objective To investigate the infection status and influential factors of ovarian cancer patients after chemotherapy. Methods The clinical data of 302 ovarian cancer patients who were treated in our hospital from January 2011 to January 2013 were collected, and analyzed by descriptive statistics and binary classification logistic regression analysis. Results The infection rate of ovarian cancer patients was 10. 6% （32/302） , the most common infection was upper respiratory infection （37.5%）. Multiple logistic regression analysis showed that venerable age （OR = 7. 692, P =0. 000）, more invasive operations （OR = 13. 074, P =0. 000） , low white blood cell count （OR = 15. 864, P =0. 000） and hospital stay 〉 21 days （ OR = 10. 033, P = 0. 000） were major risk factors of ovarian cancer patients. Conclusions Ovarian canc- er patients treated with chemotherapy were under a considerable high infection rate, which was affected by various factors.