接种兰菌净疫苗对提高一类疫苗接种及时率效果观察

Inoculation of Lantigen B vaccine on improving vaccine vaccination rate effect

目的了解兰菌净疫苗预防上呼吸道感染的效果,是否能提高一类疫苗接种及时率,为推广使用提供依据。方法采用随机、盲态将选取的1 200名婴幼儿以2:1的比例分为受试组和对照组,受试组按免疫程序接种受试疫苗,对照组不接种受试疫苗,比较两组婴幼儿从4月龄至2周岁期间上呼吸道感染发生情况及一类疫苗接种及时率。结果经χ2检验,P均﹤0.01,两组婴幼儿在上呼吸道感染和一类疫苗接种及时率方面差异比较有统计学意义,即对照组上呼吸道感染发病率高于受试组和受试组一类疫苗HepB③、OPV③、DTP③、DTP④、MV、MMR、MenA①、MenA②、JE-l①、HepA-l接种及时率均高于对照组。结论接种兰菌净疫苗能显著地降低上呼吸道感染的发生率,对提高一类疫苗的接种及时率有统计学意义。

Objective To investigate the Lantigen B vaccine to prevent infection of the upper respiratory tract effect, can improve a vaccination rate in time, provide the basis for the promotion of the use of. Methods 1 200 infants randomly, blind will be selected in a 2：1 ratio were divided into experimental group and control group, test group according to immune vaccination procedure the vaccine, while the control group was not inoculated with the vaccine, has the situation and a class of vaccine vaccination rate were compared between the two groups of infants aged from April to 2 during the age of the upper respiratory tract infection. Results By Х^2 test, P〈0.01, two groups of infants in the upper respiratory tract infection and a class of vaccination timely rate difference was very significant, In control group, the attack rate of upper respiratory tract infection was higher than that of group subjects and subjects of a class of vaccine, OPV, DTP, HepB, and DTP, MV, MMR, 4, MenA, MenA, JE-1, HepA-1 vaccination rate was higher than that of control group. Conclusion Vaccine Lantigen B vaccine can significantly reduce the incidence of upper respiratory tract infection, to improve a vaccine vaccination rate significantly.