醒脾养儿颗粒联合磷酸铝凝胶治疗小儿腹泻病的疗效观察

Clinical observation of Xingpi Yanger granule combined with aluminum phosphate gel on treating infantile diarrhea

目的:探讨醒脾养儿颗粒联合磷酸铝凝胶治疗小儿腹泻病的疗效。方法:将小儿腹泻病患儿分为治疗组(36例)和对照组(36例),对照组患儿常规给予禁食、抗病毒、静脉补液、止吐、退热、纠正水电解质紊乱、调整饮食、口服微生态制剂及其他对症治疗。治疗组在对照组治疗基础上应用醒脾养儿颗粒联合磷酸铝凝胶口服。观察两组患儿大便恢复正常时间、呕吐消失时间及热退时间。结果:醒脾养儿颗粒联合磷酸铝凝胶治疗小儿腹泻病,治疗组总有效率97.2%明显高于对照组总有效率75%,两组总效率差异有统计学意义。治疗组患儿大便恢复正常时间为(34.69±20.90)h与对照组患儿大便恢复正常时间(57.67±29.08)h比较,两组差异均有统计学意义(P<0.05)。治疗组患儿呕吐消失时间(19.83±20.01)h与对照组患儿呕吐消失时间(28.66±14.13)h比较,两组差异均有统计学意义(P<0.05)。治疗组患儿热退时间(38.00±22.67)h与对照组患儿热退时间(42.77±24.16)h比较,两组差异无统计学意义(P>0.05)。结论:醒脾养儿颗粒联合磷酸铝凝胶治疗小儿腹泻病疗效肯定,值得临床推广。

Objective： To investigate the clinical effect of Xingpi Yanger granule combined with aluminum phosphate gel in the treatment of infantile diarrhea. Methods： The children with infantile diarrhea were randomly divided into the treated group （36 cases） and the control group （36 cases）. The control group were given conventional fasting, intravenous fluids, antiemetic, antiviral, antipyretic, correct water and electrolyte disorders, diet adjustment, oral micro ecological preparations and other symptomatic treatment. The treated group used the Xingpi Yanger granule combined with aluminum phosphate gel orally based on the control group. Observation of the two groups with defecate to restore the normal time, vomiting disappeared time and the fever disappeared time. Results： The total efficiency of the treated group was 97.2% and the control group was 75%. The total efficiency differences of two groups were statistically significant （P〈0.05）. The treated group of defecate to restore the normal time was （34.69±20.90） hours and the control group of defecate to restore the normal time was （57.67±29.08） hours, the two groups had significant differences （P〈0.05）. The treatment group of vomiting disappeared time was （19.83 ± 20.01） hours and the control group of vomiting disappeared time was （28.66± 14.13） hours, the two groups had significant differences （P〈0.05）. The treated group of the fever disappeared time was （38.00± 22.67） hours and the control group of the fever disappeared time was （42.77 ±24.16） hours. There were not significantly differences between the two groups （P〉0.05）. Conclusion： Xingpi Yanger granule combined with aluminum phosphate gel in the treatment of infantile diarrhea has exact curative effect and is worthy of clinical application.