摘要
目的探讨胰岛素调节瓦斯爆炸伤大鼠中性粒细胞(PMN)凋亡的作用。方法胰岛素组和非胰岛素组的中性粒细胞(PMN)分别培养,3、6、12、18、24、36h,比较二组PMN凋亡率的变化。结果胰岛素组的PMN的凋亡率显著高于非胰岛素组(P<0.05)。结论胰岛素促进了PMN以凋亡形式的死亡。
Objective To explore the effect of insulin on PMN apoptosis in the injury caused by gas explosion rats in vitro. Methods The apoptosis change of PMN was compared when incubated at 0,3,6,12,18, 24,36 hours in the insulin group and noninsulin (control) group. Results Apoptosis rate of PMN in insulin group was significantly higher than that in control group (PM0.05). Conclusion Insulin can induce apoptosis of PMN.
出处
《中国煤炭工业医学杂志》
2013年第10期1694-1695,共2页
Chinese Journal of Coal Industry Medicine
基金
河北省科技厅河北省科技支撑计划项目(项目编号:10276110D)
关键词
瓦斯爆炸伤
细胞凋亡
中性粒细胞
胰岛素
炎症反应
大鼠
Injury caused by gas explosion
Rat
Apoptosis
Polymorphonuclear neutrophil
Insulin
Inflammatory