脐带间充质干细胞联合负压封闭引流术治疗Ⅲ、Ⅳ期压疮的临床护理

CLINICAL CARE RESEARCH ON THE UMBILICAL CORD MESENCHYMAL STEM CELLS JOINT VSD IN THE TREATMENT OF STAGE Ⅲ AND Ⅳ BEDSORE

目的探讨脐带间充质干细胞移植联合负压封闭引流术(VSD)治疗Ⅲ、Ⅳ期压疮的临床效果及护理原则。方法选取我院2011—2012年收治的Ⅲ、Ⅳ期压疮患者143例为研究对象,应用脐带间充质干细胞移植联合负压封闭引流术(VSD)治疗,观察患者愈合时间、效果及护理体会。结果 143例患者中愈合100例,显效23例,好转20例。结论脐带间充质干细胞移植联合负压封闭引流术(VSD)较单用负压封闭引流术(VSD)及常规治疗方法更好的改善Ⅲ、Ⅳ期压疮创面的愈合,避免患者组织感染,提高压疮患者的生活质量,加强护理管理在临床工作中起重要作用。

Objective To investigate the clinical efficacy of umbilical cord mesenchymal stem cell transplantation combined with VSD in the treatment of stage III and IV bedsore. Methods Totally 143 cases of stage III and IV bedsore admitted in authors hospital from 2011 to 2012 were treated by umbilical cord mesenchymal stem cell transplantation combined with VSD. The healing time, clinical efficacy of patients were observed and the nursing experience was recorded Results A total of 100 cases healed in 143 patients, 23 cases were markedly effective, 20 cases improved. Conclusions Umbilical cord mesenchymal stem cell transplantation combined with VSD therapy can more effectively accelerate the wound healing of bedsore, avoid tissue infection, improve the quality of life of patients with pressure ulcers than the treatment of epidermal growth factor alone and conventional treatment.