多烯磷脂酰胆碱注射液治疗肝功能损害的疗效观察

目的观察多烯磷脂酰胆碱注射液治疗各种病因引起的肝损害疗效。方法选择各种原因引起的肝功能损害患者119例,随机分为治疗组和对照组。治疗组:给予多烯磷脂酰胆碱注射液465 mg静滴,每日1次。对照组:给予葡醛酸钠注射液0.532 g,每日1次,疗程均为14 d。观察两组治疗前后肝功能及预后情况。结果治疗14 d后,治疗组患者症状体征改善情况优于对照组,治疗组显效及有效51例(85.0%),对照组显效及有效34例(57.6%),治疗组肝功能损害恢复情况优于对照组,两组差异显著(P<0.05)。结论多烯磷脂酰胆碱明显改善肝功能损害和临床症状,疗效显著。

Objective To observe the curative effect of Polyene Phosphatidylcholine injection on liver injury caused by different diseases. Methods 119 patients who suffered from liver injury were randomly divided into two groups： treatment group and control group. Treatment group： injected Polyene phosphatidylcholine injection 465 mg, once a day. Control group： injected sodium glucuronic Acid Injection 0.532 g, once a day; course of treatment was 14 days in two groups. The curative effect on liver function and prognosis of the two groups before and after treatment were observed. Results After 14-day treatment, patients＇ symptoms of the treatment group improved more obviously than those of the control group, and 51 cases achieved excellent effects （85.0%） in the treatment group, while 34 cases achieved excellent effects （57.6%）. The treatment group was superior to the control group in reviving Liver Injury. There were significant difference among different groups（P〈0.05）. Conclusion Polyene phosphatidylcholine injection could obviously improve liver injury and clinical symptoms, the curative effect is remarkable.