新生儿病区病原菌分布与耐药性分析

Distribution and drug resistances of pathogens in neonatal ward

目的:了解本院新生儿病区病原菌的分布及耐药性。方法:回顾性分析2011年1月至2012年10月我院新生儿病区病原菌分布及耐药性。结果:共分离出285株病原菌,分离率41.6%(285/685)。其中革兰阴性菌174株,占61.05%;革兰阳性菌110株,占38.60%;真菌1株,占0.35%。产超广谱β-内酰胺酶(ESBLs)的肺炎克雷伯菌和大肠埃希菌分别为61.02%、41.79%,检出耐甲氧西林金黄色葡萄球菌1株,耐甲氧西林凝固酶阴性葡萄球菌2株。结论:了解细菌的分布及耐药性,对合理选择抗菌药物,减少耐药菌株的产生,有效预防控制新生儿感染有重要意义。

Objective： To investigate the clinical distribution characteristics and drug resistances of pathogens in neonatal ward. Methods： The distribution and drug resistances of pathogens in neonatal ward from Jan 2011 to Oct 2012 were retrospectively analyzed. Results： A total of 285 strains of pathogens were isolated with the isolation rate of 41.6% ,which included 174 strains of gram-negative bacteria （61.05%） ,110 strains of gram-positive bacteria （38.60%） and 1 strain of fungi（0. 35% ）. The rates of Klebsiella pneumooniae, Eschericllia coli which produced ESBLs were 61.02% and 41.79%. 1 strain of methicillin-resistant Staphylococcus aureus and 2 strains of methicillin-resistant Coagulase-negative Staphylococci were detected. Conclusion： Studying the distribution and drug resistances of pathogens is important for rationally selecting antibiotics, reducing infection incidence, and decreasing the occurrence of drug resistant strains in neonatal ward.