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变应性鼻炎的舌下特异性免疫治疗研究进展 被引量:1

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摘要 变应性鼻炎(Allergic Rhinitis,AR)的变应原特异性免疫治疗(allergen-specific immunotherapy,ASIT)由英国医生Noon 于1911年首次报道用于治疗花粉症,过去曾被称为脱敏或减敏疗法.ASIT是目前惟一有可能通过免疫调节作用而改变疾病自然进程的"对因疗法",主要用于治疗AR、哮喘以及昆虫毒液过敏.该疗法传统上采用皮下注射途径,称为皮下免疫治疗(subcutaneousimmunotherapy,SCIT).1986年,英国药物安全委员会报道了几个由于皮下免疫治疗引起的死亡案例,特异性免疫治疗的安全性显得更为重要.寻找非注射途径的特异性免疫治疗是一些变态反应学者的研究方向,经过舌下-吞咽、舌下-吐出、鼻内等一些非注射途径的特异性免疫治疗的研究,目前公认舌下-吞咽途径的特异性免疫治疗(Sublingual Immunotherapy,SLIT)是安全及有效.
出处 《齐齐哈尔医学院学报》 2013年第18期2744-2746,共3页 Journal of Qiqihar Medical University
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参考文献17

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二级参考文献69

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