摘要
目的 研究血清高密度脂蛋白胆固醇(HDL-C)水平用于评价肝脏合成功能的价值.方法 用全自动生化分析仪测定对照组30例、肝病组87例血清HDL-C水平,采取t检验分析肝病组87例与对照组30例、肝病组内不同肝病与对照组、以及不同肝病之间血清HDL-C的水平差异.结果 HDL-C水平,对照组(1.28±0.20) mmol/L,肝病组(0.77±0.15)mmol/L,其中肝炎组(0.81±0.13) mmol/L,肝硬化组(0.68±0.14) mmol/L,肝癌组(0.54±0.05) mmol/L.肝病组及肝病组内肝炎、肝硬化、肝癌患者血清HDL-C水平明显低于对照组(t=15.5569、14.2463、45.4393、25.6344,均P<0.01);肝病组内肝硬化、肝癌患者血清HDL-C水平明显低于肝炎患者(t=3.6583、16.9057,均P<0.01);肝癌患者血清HDL-C水平低于肝硬化患者(t=4.4103,P<0.01).结论 肝病患者血清HDL-C水平可以反映肝脏合成功能,血清HDL-C水平越低,肝病患者肝脏合成功能受损越严重.
Objective To evaluate the clinical value of serum high density lipoprotein cholesterol (HDL-C)in the evaluation of synthetic function of the patients with liver diseases.Methods Abbott Aeroset automatic biochemical analyzer was used to detect serum HDL-C level in control group (30 cases) and liver disease group(87 cases).T test was used to analyze the differences of serum HDL-C level in liver disease group and control group,different liver disease groups and control group,and different liver disease groups.Results HDL-C level was (1.28 ±0.20)mmol/L in the control group,(0.77 ± 0.15)mmol/L in the liver disease group,and (0.81 ± 0.13)mmol/L in the hepatitis group,(0.68 ± 0.14)mmol/L in the liver cirrhosis group,(0.54 ± 0.05)mmol/L in the liver cancer group.The HDL-C level in liver disease group and hepatitis group,liver cirrhosis group,liver cancer group was significantly lower than that in the control group(t =15.5569,14.2463,45.4393,25.6344,all P < 0.01).The HDL-C level in liver cirrhosis group and liver cancer group was significantly lower than that in hepatitis group (t =3.6583,16.9057,all P < 0.01).The HDL-C level in liver cancer group was significantly lower than that in liver cirrhosis group(t =4.4103,P < 0.01).Conclusion Serum HDL-C level can be used to evaluate synthetic function of the liver,the lower of serum HDL-C level,the more serious liver synthesis function is impaired.
出处
《中国基层医药》
CAS
2013年第21期3276-3277,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
肝炎
肝硬化
肝肿瘤
高密度脂蛋白胆固醇
Hepatitis, Liver cirrhosis, Liver neoplasms
High density lipoprotein cholesterol