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B型钠尿肽在急性冠脉综合征中的临床应用及研究进展 被引量:5

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摘要 上世纪80年代,De Bold等首次从鼠心房提取液中分离出一种具有利钠和利尿作用的物质后,使人们认识到心脏除了是一个有效的弹性泵外,还是一个内分泌器官.在随后的研究中,逐渐发现了一个具有相似结构特征但基因特性不同的多肽类家族,称为钠尿肽系统(Natriuretic peptide system,NPs),目前已发现的家族成员包括:A型钠尿肽(ANP,又称心房肽)、B型钠尿肽(BNP)、C型钠尿肽(CNP)、尿扩张素(Urodilatin,一种ANP单体)及树眼镜蛇钠尿肽(DNP),其中,BNP作为心脏负荷的标志,它在心力衰竭方面的诊断作用及预后评估作用已被学界公认并广泛应用于临床,而BNP在冠心病方面的研究则方兴未艾,本文将对BNP在急性冠脉综合征(ACS)中的临床应用研究及阶段性进展做一综述.
出处 《中国基层医药》 CAS 2013年第21期3334-3337,共4页 Chinese Journal of Primary Medicine and Pharmacy
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同被引文献49

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