磁敏感加权成像对于脑微出血的诊断价值

Diagnosis value of susceptibility weighted imaging in cerebral microbleeds

目的探讨磁敏感加权成像(SWI)在脑微出血(CMBs)影像诊断中的价值。方法以SWI序列检测出CMBs的30例脑血管病患者为研究对象,通过常规MRI、T2*WI及SWI多序列对比研究,比较分析CMBs在各序列中的影像学表现、分布及检出敏感度。结果 SWI序列发现全部30例67个病灶,敏感度为100%。在SWI序列上表现为2.2～5.3mm大小不等的边界清晰、锐利的信号缺失灶。T2*WI序列共检出病灶18例51个,表现为信号缺失影,检出病灶的敏感度为76.1%。常规MRI的T1WI序列和T2WI序列共检出4例10个病灶(14.9%)。SWI序列与T2*WI序列、常规MRI序列对比差异有统计学意义(P<0.05)。结论 SWI序列对CMBs的检出敏感度高于常规序列及T2*WI序列,CMBs病灶的检出可以反映脑内微血管病变程度,对缺血性脑卒中的治疗及预后判断具有较为重要的临床应用价值。

Objective To investigate the diagnosis value of susceptibility weighted imaging（SWI）in cerebral microbleeds（CMBs）.Methods Thirty cases of cerebrovascular disease patients with CMBs detected by SWI sequence were adopted as the subjects.Multi-sequence comparative study by routine MRI,T2＊WI and SWI was used to discuss the imaging features,distribution and sensitivity of CMBs.Results The SWI sequences detected 67CMBs in 30cases,the sensitivity was 100%.CMBs in SWI sequence showed 2-5mm round or oval clear and sharp boundary low signal loss,and the sequence of T2＊WI found 51CMBs in 18cases,showing low signal loss,CMBs detection sensitivity of the T2＊WI sequence was 76.1%;CMBs detections of the usual MRI such as T1WI,T2WI sequence were 10in 4cases（14.9%）.SWI sequence,compared with T2＊WI sequence and routine MRI sequence,showed significant difference（P 0.05）.Conclusion The SWI sequence of CMBs detection sensitivity is higher than that of conventional sequence and T2＊WI sequence.CMBs lesion detection can reflect brain microvascular lesions for great clinical application value.The SWI sequence has an important role to ischemic stroke treatment and prognosis.