甲状腺功能亢进药物治疗进展

Progress in Drug Therapy for Hyperthyroidism

药物治疗甲状腺功能亢进简便、安全。在Graves病的抗甲状腺药物治疗中,除妊娠前3个月、甲状腺危象、对甲巯咪唑治疗反应差且拒绝行放射碘或手术治疗等情况外,均应选择甲巯咪唑进行抗甲亢治疗。所有甲状腺功能亢进症患者均应使用β受体阻滞剂,尤其应该使用于那些有甲亢症状的年长患者及其他静息心率超过90bpm或合并心血管疾病的患者。

Drugs in the treatment of hyperthyroidism is simple and safe. Methimazole should be used in virtually every patient who chooses antithyroid drug therapy for GD, except during the first trimester of pregnancy when Propyl-thiouracil is preferred, in the treatment of thyroid storm, and in patients with minor reactions to methimazole who refuse radioactive iodine therapy or surgery. Beta--adrenergic blockade should be given to elderly patients with symptomatic thyrotoxicosis and to other thyrotoxic patients with resting heart rates in excess of 90 bpm or coexistent cardiovascular disease.