前列地尔治疗急性脑梗死临床疗效观察

The Curative Effect of Alprostadil in the Treatment of Acute Cerebral Infarction

目的:探讨前列地尔治疗急性脑梗死的临床疗效。方法:选取在我院接受治疗的急性脑梗死患者80例,随机分为研究组与对照组各40例。研究组应用前列地尔注射液进行治疗,对照组采用丹参注射液进行治疗。结果:治疗后,两组患者的神经功能缺损程度评分(ESS)及日常生活能力(ADL)均比治疗前有明显改善(P<0.05),同时研究组的改善程度均明显优于对照组(P<0.05)。研究组的显效率、总有效率均明显高于对照组,差异具有统计学意义(P<0.05)。结论:前列地尔治疗急性脑梗死可有效促进患者神经功能的改善,提高日常生活能力,疗效显著且无严重不良反应发生,值得临床推广应用。

Objective： To investigate the clinical efficacy of alprostadil in the treatment of acute cerebral infarction. Method： 80 cases of patients with acute cerebral infarction treated in our hospital were randomly divided into study group and control group, with 40 cases in each group. Study group were treated with al- prostadil injection and control group with Danshen injection. Results： After the treatment1 the neural func- tion defect degree of the patients in the two groups （ ESSI and activity of daily living （ ADL） were improved more significantly than that before treatment （ P〈0.05） , at the same time, the degree of study group was im- proved significantly better than the control group （ P〈0.05 ）. The effectual rate and the total effective rate of the study group were evidently higher than that in the control group, the difference was statistically significant （P〈0.05 ）. Conclusion： Treating patients with acute cerebral infarction by alprostadil can effectively pro- mote the improvement of neurological function , improve their ability of daily life, the curative effect is obvi- ous and no serious adverse reactions appear , it is worthy of clinical application.