自拟滋肾活血丸联合常规疗法治疗早期糖尿病肾病30例临床观察

Effect of Zi-shen Huo-xue Pill Combined with Conventional Therapy on Eearly Diabetic Nephropathy: A Clinical observation of 30 cases

目的:观察滋肾活血丸联合常规疗法治疗糖尿病肾病的临床疗效。方法:将60例糖尿病肾病患者随机分为治疗组和对照组各30例。对照组给予胰岛素、钙拮抗剂及他汀类药物治疗;治疗组在对照组用药的基础上加用自拟滋肾活血丸治疗。两组均以8周为1个疗程,3个疗程后比较两组临床疗效、中医证候积分及生化指标改善情况。结果:总有效率治疗组为93.3%,对照组为80.0%,差异有统计学意义(P<0.05)。结论:滋肾活血丸联合常规疗法治疗糖尿病肾病疗效显著。

Objective： To observe the curative effect of Zi-shen Huo-xue pill on diabetic nephropathy. Methods： 60 pa- tients with diabetic nephropathy were randomly divided into the treatment and control groups, 30 cases in each group. Patients were treated with insulin, calcium antagonist and statins in control group, and patients in treatment group were given Zi-shen Huo-xue pill as well as the treatment of the control group. The treatment course consisted of 8 weeks, and the clinical effect, TCM syndrome and Laboratory indexes were observed in 3 treatment courses. Results： The total effective rate was 93.3% in the treatment group and 80.0% in the control group, and there was statistic significance （P〈0.05）. Conclusion： Zi-shen Huo- xue pill combined with conventional therapy can provide significant effect for diabetic nephropathy.