低温联合斜线式钠曲线和超滤曲线透析对老年血液透析患者低血压的影响

Effect of microtherm combined with oblique line sodium profile and ultrafiltration profile on hypotension due to dialysis in aged people

【目的】探讨低温联合斜线式钠曲线和超滤曲线透析对老年血液透析患者低血压的影响。【方法】选择行维持性血液透析中经常发生低血压的老年患者10例,进行自身对照,按透析的次数设单数为观察组,采用低温联合斜线式钠曲线和超滤曲线透析,双数为对照组,采用常规标准透析,观察6个月,分别300例次,统计透析时发生低血压的例次数及透析结束时超滤总量。【结果】观察组低血压发生率20%,超滤总量(3 547±369)ml;对照组低血压发生率45%,超滤总量(3 049±569)ml。低血压发生率比较差异有统计学意义(P<0.01)。平均超滤总量比较差异有统计学意义(P<0.05)。两种模式透析前后血清钠浓度、体温差异无统计学意义(P>0.05)。【结论】低温联合斜线式钠曲线和超滤曲线透析可有效的降低老年血液透析患者发生低血压的次数,增加超滤总量,提高血液透析的耐受性。

[Objective]To observe the effect of microtherm in combination with oblique line sodium profile and uhrafihration profile on hypotension due to hemo dialysis in aged patients. [ Methods] A total of 10 aged patients frequently appeared hypotension undergoing dialysis within 6 months in total of 600 person times were observed and analyzed by self control study. According to the number of dialysis the odd number was set as observation group （microtherm combination with oblique line sodium profile and uhrafihration profile, 300 person times） and the even number set as control group （standerd dialysis, 300 person times）. Incidence of hypotension and dehydration level were recorded. [ Results]The incidence of hypotension in observation group was significantly lower than those of the control group （20% vs 45%, P 〈 0.01）, and the average dehydration level in observation group was significantly higher than those of the control group （3 547 ± 369）ml vs （3 049 ±569）ml（P〈 0.05）. No significant differences were observed in body temperature and serum sodium eoneentration（P 〉 0.05）. [Conclusion ] Mierotherm combined with oblique line sodium profile and ultrafiltration profile could efficiently reduce the incidence of hypotension due to dialysis in aged patients, and increase dehydration level, These patient＇ s tolerance of dialysis was satisfactory.