毛细胞白血病4例及其相关实验室诊断分析

Four cases of hairy cell leukemia and related laboratory diagnostic analysis

目的:探讨毛细胞白血病(HCL)特征性诊断及鉴别诊断方法。方法:对4例HCL患者的临床特征及骨髓病理、组织细胞化学、白血病免疫分型、电镜等实验室检查结果进行分析。结果与结论:骨髓病理、组织细胞化学、白血病免疫分型、电镜在HCL的诊断中具有重要意义,HCL的鉴别诊断须结合患者临床特征及实验室检查。

Objective： To investigate characteristic diagnosis and differential diagnosis methods of hairy cell leukemia （ HCL） .Methods：Clinical features and bone marrow pathology , tissue chemistry , leukemia immunoph-enotyping , electron microscopy and other laboratory findings of four patients with HCL were analyzed .Results and Conclusion：Bone marrow pathology , histochemical and cytochemical , immunophenotyping of leukemia , electro microscopy play an important role in the diagnosis of HCL .The differential diagnosis of HCL should combine the clinical characteristic of and laboratory tests .