直肠癌Dixon手术后吻合口瘘相关因素的Logistic分析289例

Risk factors for anastomotic fistula after Dixon operation for rectal cancer:Analysis of 289 cases

目的:研究直肠癌患者行Dixon手术后发生吻合口瘘的相关因素.方法:回顾性分析2009-04/2013-04我院收治的289例行Dixon手术直肠癌患者的性别、年龄、伴有糖尿病、TNM分期、营养指标和吻合口距肛缘距离的情况,统计吻合口瘘的发生情况,并进行Logistic回归分析.结果:直肠癌Dixon手术后吻合口瘘的相关因素中,相对危险度最大的是TNM分期(OR=2.165),相对危险度最小的是吻合口距肛缘距离(OR=0.194).结论:直肠癌Dixon手术后吻合口瘘的相关因素中TNM分期是最大的危险因素,吻合口距肛缘距离是最大的保护因素.

AIM： To analyze the risk factors for anastomotic fistula after Dixon operation in patients with rec- tal cancer. METHODS： Clinical data for 289 patients who underwent Dixon operation for rectal cancer from April 2009 to April 2013 at our hospital were retrospectively analyzed. Factors including gender, age, diabetes, TNM stage, nutritional in- dices and the distance between the anastomosis site and anal edge were analyzed statistically. RESULTS： Among the factors possibly affect- ing the development of anastomotic fistula after Dixon operation for rectal cancer, the relative risk of TNM stage was biggest （OR = 2. 165）, and that of the distance between the anastomosis site and anal edge was smallest （OR = 0. 194）.CONCLUSION： Among the factors possibly af- fecting the development of anastomotic fistula after Dixon operation for rectal cancer, TNM stage is the biggest risk factor, and the distance between the anastomosis site and anal edge is the biggest protective factor.