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促红细胞生成素的心血管保护作用 被引量:1

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摘要 促红细胞生成素(EPo)是主要由肾脏分泌的具有多效性的一种细胞因子,传统认为其主要作用于骨髓造血细胞,和表达于红系祖细胞膜表面的特异性促红细胞生成素受体(EPoR)结合,促进红系祖细胞存活、增殖和分化,抑制其凋亡。近年研究,EPO及其受体除造血功能外,还具有广泛的非造血作用[1],通过抗细胞凋亡、抗氧化应激、抗炎、促进血管新生、促进功能恢复等,对心血管发挥保护作用。
作者 张颖轩
出处 《医学理论与实践》 2013年第19期2550-2551,共2页 The Journal of Medical Theory and Practice
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