苏姜猪四至六世代雌激素受体(ESR)基因PvuⅡ多态性分析

Polymorphism analysis of estrogen receptor gene PvuⅡ in 4-6 generation of Sujiang pig

研究了雌激素受体（ESR）基因在苏姜猪世代选育中的遗传变异情况。结果表明：在苏姜猪四、五、六3个世代中都存在AA，AB，BB三种基因型，四世代、五世代、六世代A等位基因的频率分别为71．67％，66．67％，68．33％，B等位基因的频率分别为28．23％，33．33％，31．67％。在苏姜猪3个世代检测个体中，A等位基因频率显著（P〈0．05）高于B等位基因的频率。苏姜猪3个世代中AA，AB，BB三种基因型的第1胎总产仔数差异都不显著。3个世代中AA与AB基因型的第2～4胎总产仔数差异不显著，而BB型基因的第2～4胎总产仔数显著高于AA和AB的第2～4胎总产仔数。在今后的选育中，应加强BB基因型种猪的选留，进一步提高苏姜猪窝产仔头数。

In this paper, genetic variation of the estrogen receptor （ESR） gene in Sujiang pig breeding generations were studied. The results showed that ： AA, AB and BB genotype existed in 4-6 generations. Allele frequencies of A were 71.67% , 66. 67% , 68.33% in three generations and those of B were 28.23% , 33.33% , 31.67% , respec- tively. In three generations, the frequency of A allele was significantly higher than that of B allele （ P 〈 0. 05 ）. Total first birth number of AA, AB and BB allele was not significantly different from each other and total number born of the second to the fourth birth of AA and AB allele differed from each other while that of BB was higher than AA and AB. In future breeding, the BB genotype pigs should be selected to increase the total number born of Sujiang pig.