钬激光前列腺剜除术与前列腺汽化电切术治疗良性前列腺增生的疗效比较

Comparison of the efficacy of HoLEP and TUVP for treatment of benign prostatic hyperplasia

目的比较分析钬激光前列腺剜除术(HoLEP)与前列腺汽化电切术(TUVP)对良性前列腺增生的治疗效果。方法将180例良性前列腺增生患者随机分为两组。观察组患者实施HoLEP治疗;对照组患者实施TUVP治疗。观察比较两种手术方法的安全性和疗效。结果两组患者经不同手术方法治疗后,前列腺症状评分(IPSS)、最大尿流率(Qmax)、生活质量评分(QOL)与治疗前相比均有明显改善(P<0.01),观察组改善幅度大于对照组(P<0.01);术中出血量、手术时间、导尿管留置时间和膀胱冲洗时间,观察组均小于对照组(P<0.05);观察组术后并发症发生率低于对照组(P<0.01)。结论HoLEP可降低术中出血量、减少手术时间、导尿管留置时间和膀胱冲洗时间,且并发症发生率较低,是临床治疗良性前列腺增生较理想的手术方法。

Objective To compare and analyze the treatment effects on benign prostatic hyperplasia by holmium laser enuclea- tion of the prostate （HoLEP） and transurethral vaporization resection of the prostate （TUVP）. Methods 180 patients with benign prostatic hyperplasia were divided into two groups. The obrservation group was treated with HoLEP and the control group was treated with TUVP. The safety and efficacy of the two treatments were observed and compared. Results After different treatments, IPSS, Qmax,and QOL of the two groups were significantly improved（ P 〈0.01 ） ,and the improvement of observation group was greater than that of control group（ P 〈 0.01 ）. The blood loss in operation, operation time, storage time of pipe, irrigation time of the observation group were significantly shorter than that of the control group（ P 〈 0.05 ）. The incidence rate of postoperative complications of the con- trol group was higher than that of the observation group A （ P 〈 0.01 ）. Conclusion HoLEP can reduce operation time, blood loss in operation, storage time of pipe, irrigation time and the incidence rate of postoperative complications.