养阴清热解毒法治疗Ⅱ级糖尿病足疗效观察

Efficacy Observation of Type-2 Diabetic Foot Treated with the Therapy for Nourishing Yin,Clearing Heat and Removing Toxin

目的观察养阴清热解毒法治疗Ⅱ级糖尿病足阴虚血瘀、肌肤毒聚阴疡证患者的临床疗效。方法将60例患者随机分为治疗组与对照组,各30例。对照组采用降糖、降脂、祛聚、改善患肢血供、营养神经及抗生素,溃疡创面配合换药,治疗组在对照组常规治疗的基础上配合中药养阴清热解毒,药用四妙活血汤,治疗28 d后观察临床疗效。结果治疗组疗效与对照组比较差异有统计学意义(P<0.05);治疗组患肢麻木、发凉、疼痛缓解的例数与对照组比较差异有统计学意义(P<0.05);治疗组患肢皮温及踝肱指数(ABI)治疗后与对照组比较差异有统计学意义(P<0.05)。结论养阴清热解毒法治疗Ⅱ级糖尿病足阴虚血瘀、毒聚肌肤阴疡证患者疗效显著,能缩短溃疡愈合时间,减轻患者痛苦。

Objective To observe the clinical efficacy on type -2 diabetic foot differentiated as yin deficiency and blood stagnation, and toxic retention in the skin and carbuncle of yin type, treated with the therapyfor nourishing yin, clearing heat and removing toxin. Methods Sixty cases were randomized into a treatment group and a control group,30 cases in each one. In the control group, the reducing glucose, reducing lipid and removing carbuncle were adopted to improve blood supply and nourish nerve. Additional, the wound dressing was applied with antibiotics. In the treatment group, on the basic conventional treatment as the con- trol group, the herbal medication for nourishing yin, clearing heat and removing toxin was supplemented. Simi- aoHuoxue Decoction was used. The clinical efficacy was observed in 28 days of treatment. Results The effi- cacy was different significantly in the treatment group as compared with the control group （ P 〈 0.05 ）. The difference in the case number for the symptoms alleviation such as numbness, cold and pain of the affected limb was significant in comparison between the treatment group and control group （ P 〈 0.05 ）. In the treat- ment, after treatment, the skin temperature on the affected limb and ankle brachial index were different signif- icantly as compared with the control group （P 〈 O. 05 ）. Conclusion The therapy for nourishing yin, clearing heat and removing toxin achieves the significant efficacy on type -2 diabetic foot, differentiated as yin defi- ciency and blood stagnation, and toxic retention in the skin and carbuncle of yin type. This therapy shortens the wound healing time and alleviates the sufferings of patients.