大柴胡汤治疗急性水肿型胰腺炎的临床研究

Clinical Study of Dachaihu Decoction in the Treatment of Severe Acute Pancreatitis

目的:探讨急性水肿型胰腺炎临床治疗的中医应用与疗效分析。方法:选择急性胰腺炎患者52例,根据不同治疗方案分为观察组25例和对照组27例,对照组患者给予禁食、胃肠减压、H2受体阻滞剂等常规治疗,观察组在此基础上给予大柴胡汤胃管给药治疗;观察二组患者治疗临床疗效、治疗前后APACHE II评分、其他指标与并发症。结果:观察组患者治愈率(56%)、总有效率(96%)显著高于对照组(P<0.05);治疗24h、48h、72h后APACHE II评分明显低于对照组;并发症、感染、白细胞恢复等情况均好于对照组。结论:大柴胡汤在治疗急性水肿型胰腺炎在临床疗效、安全性、经济性均有兼顾,作为该病临床治疗可靠方法正在推广。

Objective： To investigate the effect of treatment of acute edematous pancreatitis with traditional Chinese medicine. Method： 52 cases of severe acute pancreatitis were divided into observation group and control group, control group for gastrointestinal decompression, observation group added to with Dachaihu decoction, two groups were observed the clinical curative effect, before and after treatment A- PACHE II score, other index and complications. Result： The observation group cure rate and the total effi- ciency was significantly higher than that control group （ P〈0.05 ） ; 24 hours, 48 hours, 72 hours after APACHEII score was significantly lower than the control group; complications, infections, white blood cell recovery were better than the control group. Conclusion： Decoction in the treatment of acute edematous pan- creatitis in clinical efficacy, safety, economy have both, as the disease clinical treatment and reliable method is to promote.