补肾除湿化瘀汤治疗强直性脊柱炎90例

Kidney Dehumidification Huayu Decoction (KDHD) for treating with 90 cases with ankylosing spondylitis(AS)

目的:探讨补肾除湿化瘀汤在治疗强直性脊柱炎(AS)方面的疗效。方法:回顾性分析我院风湿免疫科2010年1月～2011年12月收治的强直性脊柱炎患者90例,其中,45例采用自制补肾除湿化瘀汤联合柳氮磺嘧啶治疗(观察1组),45例单纯采用补肾除湿化瘀汤治疗(观察2组),45例行传统药物柳氮磺嘧啶治疗(对照组),连续治疗三个月后观察疗效。结果:观察1组有效率为95.56%,观察2组有效率为80%,对照组有效率为82.22%,观察1组有效率明显高于观察2组(P<0.05);观察1组治疗后血沉(ESR)、C-反应蛋白(CRP)数值较其他两组下降明显(P<0.05),对照组ERS较观察2组改善明显(P<0.05)。结论:补肾除湿化瘀汤在治疗AS方面具有一定的优势,联合柳氮磺嘧啶治疗效果更佳,值得在临床工作中积极地推广应用。

Objective： To investigate the efficacy of Kidney Dehumidification Huayu Decoction（KDHD）in the treatment of ankylosing spondylitis（AS）.Methods： 90 cases with AS were treated in Division of Rheumatology of our hospital,from January 2010 to December 2011 were analyzed,45 cases were given dehumidification KDHD combined with sulfasalazine pyrimidine for treatment（observation group 1）,45 cases were given dehumidification KDHD for treatment（observation group 2）,and 45 were given sulfasalazine pyrimidine for treatment（control group）,the effects were observed after continuous treatment for three months.Results： The effective rate was 95.56% in observation group 1,the observation group 2 was 80%,and the control group was 82.22%,observation group 1 were more efficient than observation group 2（P 0.05）;the erythrocyte sedimentation rate（ESR）,C-reactive protein（CRP）values in observation group 1 decreased more significantly than the other two groups（P0.05）;ERS in the control group improved more significantly compared to the other groups（P0.05）.Conclusion： KDHD has certain advantages in the treatment of AS,and it has better therapeutic effect for combing with sulfasalazine pyrimidine,and it is worth to actively promoted in clinical.