舒血宁注射液预防长期卧床患者深静脉血栓形成的疗效观察

Curative effects of Shuxuening Injection on preventing deep vein thrombosis for long-term bedridden patients

目的探讨舒血宁注射液对长期卧床患者预防深静脉血栓形成(DVT)的临床疗效。方法 120例长期卧床患者随机分为治疗组和对照组。两组均给予常规治疗,治疗组予以舒血宁静脉输注,对照组予以低分子肝素钙皮下注射,治疗2周后评价临床疗效。结果治疗组预防深静脉血栓形成总有效率为88.3%,与对照组(90.0%)比较,差异无统计学意义(P>0.05);治疗组出血风险6.7%,与对照组(11.7%)比较,差异有统计学意义(P<0.05);两组对活化部分凝血酶时间及血小板计数影响不显著(P>0.05)。结论舒血宁注射液和低分子肝素钙均能有效预防长期卧床患者深静脉血栓形成,相对低分子肝素钙,舒血宁注射液出血风险更小,安全可靠,值得临床推广应用。

Objective To observe the ing deep vein thrombosis （DVT） for long-term bedridden patients were randomly divided clinical efficacy of Shuxuening Injection on prevent- bedridden patients. Methods 120 cases of long-term into treatment group and control group. 2 groups were given conventional treatment plus the treatment group was given intravenous Shuxuening Injec- tion while the control group was treated with subcutaneous injection of low molecular heparin calcium. The clinical efficacy in 2 groups was evaluated after 2 suits The total effective rate of preventing DVT was 88.3% in treatment group weeks. Re- and 90% in control group; the difference was not statistically significant （P〉0.05）. The risk of hemorrhage was 6.7% in treatment group and 11.7% in control group; the difference had statistical significance （P〈 0.05）. The treatments of 2 groups had little effects on thrombin time and platelet count of activated part （P〉0.05）. Conclusion The Shuxuening Injection and low molecular weight heparin calcium both can effectively prevent deep vein thrombosis of long-term bedridden patients. Compared with low molecular heparin calcium, Shuxuening Injection has less risk of hemorrhage therefore it is safer and reliable, worthy of clinical application.