5-氨基-4-酮戊酸盐酸盐光动力治疗尿道尖锐湿疣的研究

Clinical research of 5-amino-4-ketone pentanoic acid salt photodynamic in treating urethra condyloma acuminatum

目的:观察5-氨基-4-酮戊酸盐酸盐光动力疗法治疗尿道尖锐湿疣的疗效。方法:选取尿道尖锐湿疣患者216例,随机分为两组,各108例,观察组患者给予5-氨基-4-酮戊酸盐酸盐光动力疗法治疗,对照组患者给予微波治疗。结果:观察组患者的临床治愈率(96.3%)显著高于对照组(86.1%),差异具有统计学意义(P<0.05)。观察组患者的不良反应率、复发率均少于对照组,差异具有统计学意义(P<0.05)。结论:5-氨基-4-酮戊酸盐酸盐光动力疗法治疗尿道尖锐湿疣临床效果显著,是目前较为理想的治疗尿道尖锐湿疣的临床方法。

Objective：to observe the curative effect of the five - amino - 4 - ketone pentanoic acid salt photody- namic therapy for urethral condyloma acuminatum. Method： 216 cases of patients with urethral eondyloma acumina- tum were chosen, each 108 cases randomly divided into two groups, observation group patients give 5 - amino - 4 - ketone pentanoic acid hydrochloride photodynamic therapy and eontrol group patients was given the microwave treat- ment. Results： the observation group of patients with clinical cure rate is 96.3% to 86.1%, significantly higher than that of control group with statistical differences （P〈O.05）. Observation group of patients with adverse reaetion rate, re- currence rates are less than the control group, compare the differences statistieally significant （P〈O.05）. Conclusion： 5 - amino - 4 - ketone pentanoic acid hydrochloride photodynamic therapy for urethral condyloma acuminatum has re- markable clinical effect, and it is the ideal method for treatment of urethral condyloma acuminatum.