急性脑梗死患者伴发抑郁症的临床研究

A clinical study of depression in patients with acute cerebral infarction

目的:探讨急性脑梗死后患者抑郁症的发生情况、相关因素。方法:对112例急性脑梗死后患者进行临床观察,采用汉密顿抑郁量表评定其抑郁情绪状态,同时评定日常生活能力及神经功能缺损程度。结果:本研究发现,急性脑梗死后患者抑郁症的发生率为69%,抑郁症的程度与日常生活能力之间有明显关联(P<0.05),而与患者神经功能缺损程度无关联(P>0.05)。同时研究还表明,皮层下脑梗死后患者的抑郁症发生率明显高于皮层脑梗死患者。结论:抑郁症在脑梗死患者中发生率较高。日常生活能力依赖程度越高,抑郁状态越明显。早诊断、早治疗,以便有利于患者的生活能力恢复,提高生活质量。

Objective：To investigate depression in patients with acute cerebral infarction and affecting factors. Methods：In the study, 112 patients with acute cerebral infarction were examined using the Hamilton Depression Scale, Activity of Daily Living Scale and the chinese stroke scale.Result：69% of the patients were found to have depression. The degree of depression in patients was correlated with the ability of daily life, but no correlation was found between the degree of depression with patients and neurological^function. And subcortical infarction patients with depression was higher than that in cortex in patients with cerebral infarction.Conclusion＇Depression is common in patients with cere- bral infarction. The depression was related with the ability of daily life in patients with acute cerebral infarction. Hence, earlier diagnosis and treatment may be helpful for recovery of patients with life skills and improving the quality of life.