摘要
目的:分析2型糖尿病人血液中炎性因子白细胞介素6(IL-6)、肿瘤坏死因子α(TNF-α)及脂联素与正常健康个体的差异,探讨TNF-α、IL-6、脂联素与2型糖尿病的相关性。方法:检测并分析30例2型糖尿病人与11例健康个体血液中TNF-α、IL-6及脂联素的水平。结果:2型糖尿病人血中TNF-α和IL-6的水平明显高于健康个体,脂联素水平则明显低于健康个体,此种变化在肥胖患者或空腹血糖>11.1mmoL/L的糖尿病人身上更加明显。结论:2型糖尿病人血液中TNF-α和IL-6水平增加,脂联素的水平降低,且与2型糖尿病人的肥胖程度、空腹血糖水平存在相关性。
Objective： To compare TNF-α,IL-6,adiponectin between type 2 diabetes patient and normal people,to explore the relation between TNF-α,IL-6,adiponectin and type 2 diabetes.Method： To decect the TNF-α,IL-6,adiponectin of 30 patients with type 2 diabetes and 11 normal population.Result： TNF-α,IL-6 was increased while adiponectin was decreased in blood of patient,the change was more significant in the obese patients and those patients with fasting blood-glucose concentration more than 11.1mmoL/L.Conclusion： TNF-α,IL-6 was increased while adiponectin was decreased in patients with type 2 diabetes,and there is a possible relationship between blood-glucose concentration,obesity and inflammatory cytokine in type 2 diabetes patient.
出处
《河北医学》
CAS
2013年第3期327-329,共3页
Hebei Medicine
关键词
2型糖尿病
炎性因子
肥胖症
血糖
Type 2 diabetes
Inflammatory cytokine
Obesity
Blood-glucose
