复方α-酮酸片治疗慢性肾衰竭的疗效观察

The Effect of Ketosteril in the Treatment of Chronic Renal Failure

目的:观察复方α-酮酸片治疗慢性肾衰竭的临床疗效。方法:54例患者随机分为对照组和实验组,对照组给予常规治疗,实验组在常规治疗基础上加用复方α-酮酸片,持续治疗8周,观察治疗前后两组生化指标的变化。结果:治疗后,实验组中TC、TG、SCr、BUN、血磷、PTH明显降低,ALB及血钙值明显提高,其差异具有统计学意义(P<0.05);与对照组比(较,各指标变化仍明显(P<0.05)。结论:复方α-酮酸片可有效保护肾功能,延缓肾脏衰竭进程。

Objective： To observe the effect of ketosteril in the treatment of chronic renal failure.Method： 54 patients with chronic renal failure were randomly divided into 2 groups.The patients in control group were underwent conventional therapy,while patients in the experiment group were underwent ketosteril added by vein.Treatment courses lasted 8 weeks in both groups.Biochemical indicators were detected before and after therapy.Result： After the therapy,the values of BUN,Scr,TC,TG,phosphorus and PTH were reduced,while the ALB and hypocalceamia were promoted significantly in the experiment groups（P〈0.05）.And there were significant difference between the values in experiment group and those in control group（P〈0.05）.Conclusion： The ketosteril treatment for the chronic renal failure can protect the renal function and delay the process of renal failure.