难治性肺炎支原体肺炎的检验结果分析

Detection results analysis of refractory mycoplasma pneumoniae pneumonia

目的 探讨检验结果对难治性肺炎支原体肺炎的治疗价值.方法 将应用大环内酯类药物治疗至少7d,病情仍恶化者定义为难治性肺炎支原体肺炎病例,山西大医院2012年1月至2012年11月收治的62例小儿肺炎支原体肺炎,被分为普通肺炎支原体肺炎32例和难治性肺炎支原体肺炎30例,均测定其C-反应蛋白（CRP）、降钙素原（PCT）、乳酸脱氢酶（LDH）水平.结果 普通肺炎支原体肺炎、难治性支原体肺炎的CRP值分别为（7.00±4.34） mg/L、（6.16±2.79） mg/L,差异无统计学意义（P＞0.05）,普通肺炎支原体肺炎、难治性肺炎支原体肺炎的PCT值分别为（0.056±0.007） ng/L、（0.195±0.102） ng/L,差异有统计学意义（P＜0.05）,普通肺炎支原体肺炎、难治性肺炎支原体肺炎LDH值分别为（261.50±36.92） IU/L、（389.96±81.81） IU/L,差异有统计学意义（P＜0.05）.结论 PCT、LDH是判断难治性肺炎支原体肺炎炎症反应轻重的可靠指标,比CRP更敏感.

Objective To investigate the detection results of refractory mycoplasma pneumoniae pneumonia （RMPP） in children,so as to recognize and treat the disease earlier.Methods Sixty-two cases of MPP admitted in our hospital from January 2012 to November 2012 were selected.They were divided into two groups,32 cases in ordinary MMP group and 30 cases in RMMP group.The diagnostic criteria of RMPP：the patient ＇s condition still deteriorates after treatment with macrolides for more than 7 days.The serum levels of C-reactive protein （CRP）,procalcitonin （PCT）,lactic dehydrogenase （LDH） were detedcted.Results The CRP level in the serum of the children with ordinary MPP and RMPP was （7.00 ±4.34） mg/L and （6.16 ±2.79） mg/L,respectively,there was no significant difference between the two groups （P ＞ 0.05）.The PCT level in the serum of the children with ordinary MPP and RMPP was （0.056 ±0.007） ng/L and （0.195 ±0.102） ng/L,respectively,there was significant difference between the two groups （P ＜ 0.05）.The LDH level in the serum of the children with ordinary MPP and RMPP was （261.50 ±36.92） IU/L and （389.96 ±81.81） IU/L,respectively,there was significant difference between the two groups （P ＜ 0.05）.Conclusions PCT,LDH is more sensitive than CRP in inflammatory response of RMMP.