2Sun Y, Jin K, Peel A, et al. Nenroglobin protects the'brain from ex- perimental stroke in vivo [J]. Proc Natl Aead Sci USA,2003,100(6): 3497.
3Khan AA, Wang Y, Sun Y, et al. Neuroglobin-overexpressing transgenie mice are resistant to cerebral and myocardial ischemia [J]. Proc Natl Acad Sci USA,2006,103(47):17944.
4Brunori M, Giuffre A, Nienhaus K, et al. Neuroglobin, nitric oxide, and oxygen: functional pathways and conformational changes [J]. Pl:c Natl Acad Sci USA,2005,102(24):8483.
5Fordel E, Thijs L, Martinet W, et al. Neuroglobin and cytoglobin.overexpression protects human SH-SY5Y neuroblastoma cells a- gainst oxidative stress-induced cell death [J]. Neurosci Lett,2006, 410(2): 146.
6Zbang WH, Wa1:g It, Wang X, ct al. Nortriptyline protects mito- cbondria and reduces cerebral ischemia/hypoxia injmy [J]. Stroke, 2008,39(2):455.
7Liu J, Yu Z, Guo S, et al. Effects of neuroglobin overexpression on mitochondrial function and oxidative stress following hypoxia/re- oxygenation in cultured neurons[J]. J Neurosci Res,2009,87(1):164.
8Lee S 1f, Kim M, Yoon B W, et al. Targeted hsp70.1 disruption in- creases infarction volume 'after focal cerebral ischemia in mice[J]. Stroke,2001,32(12):2905.
9Xu L, Emery JF, Ouyang YB, et al. Astrocyte targeted overcxpres- sion of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia[J]. Glia,2010,58(9): 1042.
10Sun Y, Ouyang YB, Xu L, et al. The carboxyl-terminal domain of inducible Hsp70 protects from ischemic injury in vivo and in vitro [J]. J Cereb Blood Flow Metab,2006,26(7):937.
6Delano BG.Improvements in quality of life following treatment with r-HuEPO in anemic hemodialysis patients.Am J Kidney Dis, 1989, 14(1):14.
7Piccoli A,Malagoli A,Komninos G,et al.Subcutaneous epoetin-alpha every one,two,and three weeks in renal anemia.J Nephrol,2002,15(5): 565.
8Vogel V, Kramer H J, Backer A, et al.Effects of erythropoietin on en- dothelin-1 synthesis and the cellular calcium messenger system in vascular endothelial cells.Am J Hypertens, 1997,10:289.
6Felberg RA, Burgin WS, Grotta JC.Neuroprotection and the ischemic cascade[J]. CNS Spectrums, 2000,5 (3) : 52-58.
7Tanaka M.Pharmacological and clinical profile of the free radical scavenger edaravone as a neuroprotective agent[J]. Nihon Yakurigaku Zasshi ,2012,119(5) : 301-308.
8Takabatake Y,Uno E,Wakamatsu K,et al.The clinical ef- fect of combination therapy with edaravone and sodium ozagrel for acute cerebral infarction[J].No To Shinkei, 2003, 55(7) : 589-593.
9Jadad AR,Moore RA,Carroll D,et al.Assessing the quali- ty of reports of randomized clinical trials : is blinding nec- essary[J].Control Clin Trials,2015,36( 1 ) : 1-12.
10Adama HP Jr,Adama RJ,Brott T,et al.Guidelines for the early management of patients with ischemic stroke[J].Stroke, 2013,44 (4) : 1056-1083.
