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MicroRNAs与头颈鳞状细胞癌

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摘要 MicroRNAs （miRNAs）参与头颈鳞状细胞癌（head and neck squamous cell carcinoma,HNSCC）转录后的基因调控,与HNSCC的发生密切相关.有些miRNAs在HNSCC中表达上调,表现为癌基因的作用；而有些miRNAs在HNSCC中表达下调,表现为抑癌基因的作用.研究HNSCC中miRNAs表达异常及其作用机制,对头颈肿瘤的诊断和治疗具有重要意义.
作者 王茹 房居高
机构地区 [
出处 《国际耳鼻咽喉头颈外科杂志》 2013年第4期215-218,共4页 International Journal of Otolaryngology-Head and Neck Surgery
基金 北京市自然科学基金资助项目（7112029）
关键词 微RNAS (MicroRNAs) 头颈部肿瘤(Head and NECK Neoplasms) 癌 鳞状细胞(Carcinoma Squamous Cell)
分类号 R739.91 [医药卫生—肿瘤]
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参考文献27

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共引文献27

国际耳鼻咽喉头颈外科杂志
2013年 第4期

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