多巴胺与多巴酚丁胺加呋噻米治疗顽固性心力衰竭疗效分析

The Efficacy of Dopamine and Dobutamine in Treatment of Refractory Heart Failure

目的：探讨小剂量多巴胺与多巴酚丁胺加呋噻米治疗顽固性心力衰竭临床疗效及对心功能的影响。方法：选择2008年1月-2012年1月在我科住院的顽固性心力衰竭患者48例，随机分成2组：常规组治疗7天，治疗组以小剂量的多巴胺＋多巴酚丁胺与呋噻米治疗7天。结果：常规组显效8例，有效8例，治疗组显效12例，有效11例，治疗组治疗后的SV、LVEF较常规组治疗后改善更明显（P〈0．05）。结论：小剂量多巴胺与多巴酚丁胺加呋噻米治疗难治性心衰能明显改善心功能，是一种有较高的临床价值的治疗方法。

Objective：To discuss the effect on the treatment of refractory heart failure and the cardiac function with small dose of dopamine and dobutamine adding furosemide. Methods：Data was made in 48 patients with refractory heart failure in our hospital from January 2008 to Janu- ary 2012, there were 27 male patients and 21 female patients, the age was between 54 and 78（66.38 ± 7.35） years old. They were divided into two groups, one group was treated with normal method for 7 days and the other one was treated with small dose of dopamine and dobutamine adding furosemide. Results：8 patients in the group treated with normal method played an excellent efficacy and all of them were effective,12 pa- tients in the dopamine group also played an excellent efficacy and 11 of them were effective, the efficacy on SV and LVEF of dopamine group wasmere obvious than the normal treatment greup（p 〈 O. 05）. Conclusion：treatment of refractory heart failure with small dose of dopamine and dobutamine adding furosemide can improve the cardiac function and it can be a valuable method on clinical treatment.