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罗库溴铵在非体外循环下冠状动脉搭桥术患者麻醉中的应用

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摘要 目的:研究罗库溴铵在非体外循环下冠脉搭桥术患者的临床药效及气管插管的效果,以及对血流动力学的影响。方法:选择50例非体外循环下冠脉搭桥术患者,并随机分为2组,A组(n=25)给予罗库溴铵0.6 mg/㎏和B组(n=25)给予维库溴铵0.1 mg/㎏。分别记录给药后心率、收缩压、舒张压和平均动脉压及ST段的变化。结果:罗库溴铵起效时间比维库溴铵快,2组血流动力学数据有不同程度变化,但无显著性差异。结论:非体外循环下冠脉搭桥麻醉的重点在于确保麻醉平稳,并要求麻醉达到一定深度,避免加重心肌缺血,维持并改善心肌的氧供氧耗的平衡。罗库溴铵0.6 mg/㎏可安全地应用于非体外循环下冠脉搭桥术患者,无心肌缺血改变。罗库溴接和维库溴铵都是对循环无显著影响的非去极化肌松药。
出处 《中国伤残医学》 2013年第10期130-131,共2页 Chinese Journal of Trauma and Disability Medicine
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