摘要
目的：建立养心安神丸的质量标准。方法：采用TLC对养心安神丸中的五味子、丹参、首乌藤进行定性鉴别；采用HPLC测定五味子甲素和五味子乙素的含量。结果：养心安神丸中五味子、丹参、首乌藤的的薄层色谱鉴别斑点清晰，分离较好。五味子甲素在0．242～4．84μg呈良好的线性关系（r=0．9992），平均回收率为98．48％（RSD1．03％）；五味子乙素在0．110～2．21μg呈良好的线性关系（r=0．9994），平均回收率为97．10％（RSD1．03％）。结论：建立的质量标准简便可行，可用于养心安神丸的质量控制。
Objective： To establish the quality standard for Yangxinanshen pills. Method： Fruetus Schisandrae Chinensis, Salvia miltrorrhiza and Caulis Polygoni Multiflori in Yangxinanshen pills were identified by TLC. The deoxysehizandrin and sehisandrin B were determined by HPLC. Result： By TLC, the spots of three herbal drugs were well separated and without interference. Deoxyschizandrin showed a good linear relationship in the range of 0. 242-4.84 μg （r =0. 999 2） and the average recovery was 98.48% （RSD 1.03% ）. Schisandrin B showed a good linear relationship in the range of 0. 110-2.21 μg （r = 0. 999 4） by HPLC. The average recovery was 97. 10% （RSD 1.03% ）. Conclusion： The method is simple, reliable and accurate, which can be applied to quality control of Yangxinanshen pills.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第21期93-95,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(81073024)
