哈乐联合少腹逐瘀汤治疗慢性非细菌性前列腺炎/慢性骨盆疼痛综合征

Clinical Observations on Harnal Capsule Combined with Shaofu Zhuyu Soup in Treating Chronic Abacterial Prostatitis/Chronic Pelvic Pain Syndrome

目的:探讨哈乐联合少腹逐瘀汤治疗慢性非细菌性前列腺炎/慢性骨盆疼痛综合征(chronic abacterial prostatitis/chronic pelvic pain syndrome,CABP/CPPS)的临床效果。方法:选择2008年9月至2012年10月甘肃中医学院附属医院就诊的CPPS患者130例,按照就诊的先后次序随机分为A,B两组,每组65例,A组给予盐酸坦索罗辛缓释(哈乐)胶囊治疗,B组给予哈乐联合少腹逐瘀汤治疗,观察比较两组的治疗效果,观察指标:慢性前列腺炎症状评分、前列腺液白细胞计数、卵磷脂小体及尿流率变化。结果:B组总有效率明显高于A组,差异有统计学意义(P<0.05);治疗后B组的前列腺液白细胞计数和NIH-CPSI临床症状评分明显低于A组,差异有统计学意义(P<0.05);治疗后B组卵磷脂小体()明显多于A组,差异均有统计学意义(P<0.05);治疗后A组和B组患者尿流率较治疗前均有增加,差异具有统计学意义(P<0.05);治疗后A组和B组患者尿流率比较无统计学差异。结论:少腹逐瘀汤可显著提高哈乐治疗慢性骨盆疼痛综合征的临床疗效,且治疗显效时间明显缩短。

E Objective： To investigate the effect of harnal capsule combined with Shaofu Zhuyu soup in treating chronic abaeterial prostatitis/chronie pelvic pain syndrome. Method： One hundred and thirty patients of CPPS from September 2008 to October 2012 were randomly divided into A and B group, 65 cases in each group. A group received the treatment of harnal capsule, the B group received the treatment of harnal capsule combined with Shaofuzhuyu soup. Observe and compared the clinical effect of the both groups. The evaluating indexes included the change of the scores of NIH-CPSI, leukocyte count and lecithin corpuscles in prostatic fluid, peak flow. Result： The total effective rate in B group was higher than A group, and there was significant difference in both groups （P 〈 0.05）. The scores of NIH-CPSI, leukocyte count in B group were significantly lower than those in A group after treatment, and there was significant difference in both groups （P 〈 0.05）. The cases with lecithin corpuscles （） in B group were more than those in A group, and there was significant difference in both groups （P 〈 0.05）. The peak flow and mean flow increased after treatment in both group, and there was statistically differences. There was no peak flow and mean flow statistically differences after treatment between A and B group, presenting similarities in Conclusion： Shaofu Zhuyu soup can significantly improve the clinical effect of Chronic abacterial prostatitis/chronic pelvic pain syndrome, and the effective time was significantly shorter.