养肺保元胶囊治疗慢性阻塞性肺疾病

Clinical Effects of Yangfei Baoyuan Capsule on Patients with Chronic Obstructive Pulmonary Disease

目的:探讨养肺保元胶囊对慢性阻塞性肺疾病(COPD)临床稳定期临床疗效。方法:选择COPD患者120例,随机分为治疗组60例与对照组60例,所有病例均给予常规治疗,治疗组在常规治疗基础上加用养肺保元胶囊,疗程为3个月,综合观察两组治疗前后肺功能、BODE指数、1年内慢性性肺疾病急性发作期发作(AECOPD)次数。结果:治疗后两组呼吸困难评分、第1秒用力肺活量占预计值的百分比(FEV1%Pred)、第1秒用力肺活量占用力肺活量百分比(FEV1/FVC%)明显改善,治疗组呼吸困难评分、BODE总分、1秒用力呼气量(FEV1)与对照组比较水平显著增加(P<0.05),1年内急性发作及住院次数明显优于对照组(P<0.05)。结论:养肺保元胶囊显著改善COPD稳定期患者FEV1水平、BODE指数,减少AECOPD发作次数,对COPD患者稳定期疗效显著。

Objective： To observe the clinical effects of Yangfei Baoyuan capsule on stablestage patients with chronic obstructive pulmonary disease （COPD）. Method： one hundred and twenty subjects were randomly divided into observation group and control group （n = 60 each）. Both groups were adopted the conventional drug therapy. The observation group was given Yangfei Baoyuan capsule, treatment for 3 months. The lung function, BODE index and 1 year attack frequency of acute exacexbation of chronic obstructive pulmonary disease （AECOPD） were measured to evaluated the quality of life. Result： The observation group showed significant improvement compared with the control group in the following indexes： forced espiratory volume in 1 second （FEV1 ）, modified medical research council scale （mMRC） and BODE index were more lower than those in the control group （P 〈 0.05）. 1 year number of AECOPD and hospital treatment is superior to the control group. Conclusion： Yangfei Baoyuan capsule can significantly improve the lung function, AECOPD and BODE index in patients with COPD, and treatment of patients with COPD has significant curative effect.