摘要
目的:考察味连须微丸的制备工艺。方法:利用挤出-滚圆法制备微丸,采用单因素考察和正交设计筛选最优处方及工艺。结果:所得微丸的制备工艺简单,大小均匀,载药量大而均匀,适于工业化生产。
Objective: To optimize the preparation technique of Fibrous Root Coptidis pellets.Methods: The pellets were prepared by extrusion-spheronization method based on the studies of influential factors,and optimal formulation was obtained by orthogonal design.Results:Prepared pellets have such advantages as simple technique,uniformity in diameters,high drug content and useful for large-scale production.
出处
《中兽医医药杂志》
2013年第2期9-11,共3页
Journal of Traditional Chinese Veterinary Medicine
基金
石柱黄连规范化种植基地及其SOP优化升级研究(2011BAI13B02-1)
关键词
味连须
微丸
制备工艺
挤出滚圆法
Fibrous Root Coptidis
pellets
preparation technology
extrusion-spheronization method