2009—2011年我院住院药房抗生素使用情况分析

Analysis of Antibiotics Application in the Dispensary for Inpatients

目的了解我院住院病人抗生素的应用状况及趋势。方法采用WHO推荐的限定日剂量值分析法,统计我院住院药房2009—2011年抗生素类药物的用药金额、用药频度、药品限定日费用(DDC)和年均增长率(AARG)。结果住院药房3年抗生素销售金额、药品总销售金额、AARG以及抗生素在药品总金额中的百分比,呈年度递增趋势;青霉素类、头孢菌素类、抗真菌药消耗金额排序居前,青霉素类、头孢菌素类仍为抗感染药物首选,DDC较高,但呈现出下降趋势。抗真菌药所占比例略高。结论我院近年住院药房抗生素应用基本合理,但应进一步加强对抗生素使用的监督管理,以保证合理用药。

Objective To investigate situation and tendency of antibiotics application in the dispensary for inpatients in our hospital. Methods Data of medication cost, medication frequency, defined daily cost （DDC） and average annual growth rate （AARG） in our dispensary for inpatients from 2009-2011 was collected by analysis method of defined daily dose value recommended by WTO. Results The medication cost of antibiotics, -total medication cost, AARG and the ratio of medication cost of antibiotics to total medica- tion cost in the dispensary for inpatients in three years increased progressively year by year; penicillins, cephalosporin and antifungal drugs were used more frequently, and penicillins and cephalosporin were the first choice for anti - infective drugs. High amount of DDC decreased year by year. The proportion of antifungal was slightly higher. Conclusion The antibiotics application in our dispensary for inpatients should be reasonable, but further supervisory management should be strengthened to ensure the rational administration.