高能中波紫外线联合复方甘草酸苷治疗白癜风疗效分析

Therapeutic efficacy of high-energy UV combined with compound glycyrrhizin on vitiligo

目的观察高能中波紫外线联合复方甘草酸苷治疗稳定期白癜风的疗效和不良反应。方法选择皮肤科门诊就诊的稳定期白癜风患者90例,按半随机方法分为两组:治疗组45例,共计皮损209片,采用高能中波紫外线联合复方甘草酸苷治疗;对照组45例,共计皮损203片,采用单纯高能中波紫外线治疗,共治疗3个月。结果治疗组总有效率为82.2%,对照组为53.3%,治疗组疗效明显优于对照组,差异有统计学意义(P<0.01)。结论高能中波紫外线联合复方甘草酸苷治疗白癜风的早期疗效显著,患者依从性好,不良反应少。

Objective To observe the clinically therapeutic efficacy of high-energy ultraviolet-B （UV-B） combined with compound glyeyrrhizin on vitiligo and its safety. Methods A total of 90 patients with stable vifiligo were divided into trial group and control group at semi-random. The trial group （ n = 45, number of lesions = 209） was treated with high-energy UV-B plus compound gly- cyrrhizin for three months, and the control group （ n = 45, number of lesions = 203 ） with high-energy UV-B alone for three months. Results The effect rate of the trial group was 82.2% , superior to that of the control group （53.3%）. There was a statistically significant difference between the two groups （P 〈 0.01 ）. Conclusion The combination of high-energy UV-B and compound gly-cyrrhizin is safe, and therapeutically effective on the patients with stable vitiligo.