综合干预措施在提高阻塞性睡眠呼吸暂停低通气综合征患者生活质量中的应用

Application of Comprehensive Interventions on Quality of Life in Patients with OSAHS

目的探讨综合干预措施对提高阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)患者生活质量的影响。方法经多导睡眠监测(polysomnography,PSG)确诊的110例中重度OSAHS患者,按随机数字表法将其分为观察组60例和对照组50例,在给予双侧扁桃体剥离、悬雍垂腭咽成形手术的基础上,观察组患者给予综合干预措施,对照组患者给予疾病相关知识教育和改善不良生活习惯的建议,两组患者在干预后1、3、6个月采用生活质量量表(medical outcomes survey short form questions,MOS SF-36)对干预后患者的生活质量进行测评。结果综合干预措施对提高中重度OSAHS患者的生活质量有显著效果。结论综合干预措施能明显减轻中重度OSAHS患者的临床症状,提高患者的生活质量,在临床上有重要的应用价值。

Objective To explore the function of comprehensive interventions on quality of life in patients with obstructive sleep apnea-hypopnea syndrome （OSAHS）. Methods Diagnosed by polysomnography, totally 110 adults with moderate to severe OSAHS were randomly divided into control group（n=50） and observational group（n = 60）. Based on bilateral tonsillectomy and uvulopalatopharyngoplasty, patients in the observational group received comprehensive interventions. Patients in the control group were given advices about lifestyle improvement and disease related health education. The medical outcomes survey short form question, MOS SF-36 was used to evaluate the quality of life of both groups at 1 month, 3 months and 6 months after intervention. Results Effects of comprehensive interventions on the quality of life for patients with moderate to severe OSAHS were remarkable. Conclusion With great clinical applica- tion value, treatment of surgical and comprehensive behavior interventions can significantly relieve the clinical symptoms and improve their quality of life for patients with moderate to severe OSAHS.